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After first graduating in Chemistry/Statistical Analysis at Birkbeck College, University of London in 1981 (achieved part-time whilst employed as a scientific officer at Guy’s Hospital Poisons Unit), Prof. Grootveld completed his PhD degree research programme on bioanalytical chemistry and metallodrugs in 1985 at the same institution and then conducted post-doctoral work on the analysis of ‘markers’ of free radical activity in biofluids at King’s College, University of London for 2 years. He then spent 2.5 years lecturing and conducting research work at the Polytechnic of North London prior to taking up a Lectureship in Clinical Chemistry at St. Bartholomew’s and the Royal London School of Medicine and Dentistry in 1989, where he subsequently became Senior Lecturer and then Reader in Chemical Pathology. Later, he transferred to London South Bank University where he was also Reader in Chemical Pathology, and Director of their MSc Forensic Science course. He was then appointed Professor of Chemical Pathology and Biomedical Materials at the Institute for Materials Research and Innovation (IMRI), University of Bolton where he established and directed a Master’s course in Medical and Healthcare Devices which was the first of its kind available in the UK. Recently, he took up the position of Professor of Bioanalytical Chemistry at Leicester School of Pharmacy, 51Âþ»­, where he is also Head of the Chemistry for Health/Bioanalytical Sciences Research Group. He was Visiting Professor of Clinical Chemistry at Queen’s University Belfast from 2001-2005. Prof. Grootveld is the author of more than 160 full, peer-reviewed research publications in reputable international scientific and/or clinical journals, 25 reviews/book chapters, and more than 250 refereed conference contributions. He is also the Editor and author of 4 books. Since 1987, he has attracted more than £8,000,000 of external research funding. In 2020 alone, Prof. Grootveld achieved 20 full-length research publications in reputable scientific or clinical journals, along with 4 reviews and 1 edited/authored book. Prof. Grootveld was the very first researcher to apply non-stationary, low-field benchtop nuclear magnetic resonance (NMR) facilities to the multicomponent analysis of biological fluids such as human urine as early as 2014, which was long before anyone else had attempted to claim or exploit this development.  

Prof. Grootveld is a Fellow of the Royal Society of Biology, the Royal Society of Chemistry, and the Institute of Biomedical Sciences. He is also a Fellow of the Royal Statistical Society. His is also a member of the Editorial Board of the highly-prestigious MDPI journal Metabolites, and is currently serving as a lead guest Editor for Frontiers in Nutrition. He organised and the very first international symposium regarding the applications of high-resolution NMR techniques to the oral science area (IADR conference, New Orleans, USA, March 2007). His administrative duties have included student recruitment, budget and policy issues, together with successful programme development. Previously, he also held the position of Honorary Associate Clinical Professor at Warwick Medical and Dental School, University of Warwick for a 3-year period. Prof. Grootveld was also shortlisted as one of the top 5 PhD supervisors in the whole of the UK by FindAUniversity Ltd. in 2020.

Research activities: Attraction of research funding from research councils, EU, medical charities, industrial sources, etc.; operation and management of such externally-funded research programmes; publication of research data in reputable scientific/clinical journals; supervision of post-doctoral and postgraduate staff; generation and management of research grant research outputs.

Medicinal Chemistry

Bioanalytical Chemistry

.

• Biomolecular investigations of the aetiology and pathogenesis of inflammatory and cardiovascular diseases;
• The role of ‘oxidative stress’ in the pathogenesis of human diseases;
• The multicomponent high-resolution NMR analysis of biofluids and tissues for diagnostic, prognostic and forensic purposes;
• Biomedical, bioanalytical and metabolomic investigations of oral diseases and the therapeutic activities of oral healthcare products;
• The development and application of techniques for the monitoring of drugs of both clinical and forensic interest;
• Synthesis, applications and mechanisms of action of drugs and metallodrugs;
• Pharmacology and pharmacodynamics (both clinical and forensic aspects);
• The biological and medicinal chemistry of reactive oxygen species (ROS), together with the detection and pathological significance of products derived from their reactions, both in vitro and in vivo;
• Biological inorganic chemistry, for example the ‘speciation’ of metal ions in biofluids and tissues;
• The development and testing of novel biomaterials and biosensors;
• Bio- and chemometrics, and metabolomics, including NMR-based exploratory data analysis and pattern recognition techniques;
• Design, development and testing of metal alloy oral and joint prostheses;
• The experimental design of clinical trials and statistical analysis of data derived therefrom;
• Research ethics of clinical investigations.

Delivery of lectures on Clinical Trials, Statistical Analysis of Experimental Data, Chemical Pathology, Bioanalytical and Analytical Chemistry, and Biomedical Materials; Module Leader for Forensic Science Module ‘Molecules Have Fingerprints Too’.

• Fellowship of the Royal Society of Chemistry
• Fellowship of the Society of Biology
• Chartered Biologist
• Fellowship of the Institute of Biomedical Sciences
• Fellowship of the Royal Statistical Society.

BSc Forensic Science (Molecules have Fingerprints Too)

• Prof. Grootveld is the author of 109 full, refereed research publications in reputable international scientific and/or clinical journals, 17 reviews and more than 200 refereed conference contributions. Since 1987, he has attracted more than £5,700,000 of external research funding.
• Honorary Associate Clinical Professor at Warwick Medical and Dental School, University of Warwick for a 3-year period.
• Visiting Professor of Clinical Chemistry at Queen’s University Belfast from 2001-2005.
• Organised and chaired the very first international symposium regarding the applications of high-resolution NMR techniques to the oral science area (IADR conference, New Orleans, USA, March 2007).

Member of the European Tooth-Whitening Committee.

• Fellowship of the Society of Biology and the Royal Society of Chemistry.
• Member of the Institute of Biomedical Sciences

More than 200 refereed conference contributions.

Consultant for a very wide range of healthcare, oral healthcare, pharmaceutical and food companies/corporation.

Editorship of Reputable Scientific and Clinical Journals:

Member of the Editorial Boards of Current Metabolomics; International Journal of Medical and Clinical Research; Bio- Analytical Technique; SOJ Pharmacy & Pharmaceutical Sciences; Guest Editor for Computational and Mathematical Methods in Medicine.